Rac signaling in breast cancer: A tale of GEFs and GAPs
نویسندگان
چکیده
منابع مشابه
Regulating Rac in the Nervous System: Molecular Function and Disease Implication of Rac GEFs and GAPs
Rho family GTPases, including RhoA, Rac1, and Cdc42 as the most studied members, are master regulators of actin cytoskeletal organization. Rho GTPases control various aspects of the nervous system and are associated with a number of neuropsychiatric and neurodegenerative diseases. The activity of Rho GTPases is controlled by two families of regulators, guanine nucleotide exchange factors (GEFs)...
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ژورنال
عنوان ژورنال: Cellular Signalling
سال: 2012
ISSN: 0898-6568
DOI: 10.1016/j.cellsig.2011.08.011